
I design artificial cells for new-to-nature photosynthesis — and teach protein language models to read and write the code of fluorescence.
My work lives where light meets life — building cells that have never existed, to capture light in ways evolution never tried.
I'm a doctoral researcher at the University of Cambridge, in the Department of Chemistry, reimagining photosynthesis from first principles: synthetic compartments engineered to intercept light and drive new-to-nature chemistry.
Before Cambridge I trained across four labs and three continents — nanobody screening at Harvard, protein nanopore engineering at Oxford, photoenzymes at Manchester, and cell-free synthetic biology at Tsinghua — and increasingly at the frontier of machine learning for biology, fine-tuning protein language models to understand and design fluorescent proteins.
Across all of it I'm chasing the same thing: the elegant translation of light into life.
First-author work at the ICML 2026 AI for Science workshop. A LoRA fine-tune of ESM2 that learns the grammar of fluorescent proteins to predict spectra and propose new variants.
Doctoral project — synthetic cell-like compartments that intercept light and drive carbon chemistry along non-natural pathways.
A growing record across chemistry, synthetic biology, and ML for the life sciences.
A LoRA fine-tune of ESM2 that learns the grammar of fluorescent proteins. GitHub ↗
A harmonized hybrid of physical, chemical, and biological catalysis for CO₂ valorization.
Contributing author (listed as Zhijie Su).
Chemical & synthetic biology — artificial cells for new-to-nature photosynthesis: compartments that intercept light and drive non-natural chemistry.
High-throughput discovery of nanobodies by templated emulsification for neuroblastoma therapies — CDR-randomized generic libraries, genotype–phenotype association in droplets, and click-chemistry bioconjugation of hydrogel beads.
Extended long β-barrel nanopores for protein sensing: electrophysiology and single-channel recording, expression and purification of Protective Antigen, and bioinformatic pore design.
Engineered fatty-acid photodecarboxylase to convert fatty acids into fuels under blue light — broadened substrate scope (C4–C12) and built real-time CO₂/NADPH kinetic assays.
Built an enzymatic CO₂-fixation pathway driven by thylakoid NADPH/ATP regeneration and quantum-dot photocatalysis, with MOF-immobilized enzymes for long-term illumination.
Department of Chemical Engineering.
To be announced soon.
I also have an Actor dream